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Management:  Prostate
Prostate Seed Implants
Eligibility: Seed Implants
High Dose Rate (HDR)
Physicians
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Eligibility: Seed Implants

Your physician will review with you whether you may be a candidate for a prostate seed implant.  This will depend on many factors:

Your Medical Health
As patients will require anesthesia for the seed implant, the patient will to be medically fit to tolerate anesthesia.  A thorough review of your past medical history including recent heart problems, especially heart attacks, strokes, use of blood thinners, breathing problems, heavy smoking, etc.

Your Anatomy
Your radiation oncologist will determine if your pelvic structure is suitable for a prostate seed implant by carrying out an ultrasound or CT scan to determine possible interference of the pelvic bones in accessing the prostate during surgery.  

Your Prostate Size
The number of seeds implanted into the prostate depends on the size of the gland.  The average prostate size increases with age but the average prostate for a 65 year old white male is roughly 35-50cc.  The larger the gland, the more seeds that need to be implanted and as such the greater the overall radioactivity.  This leads to greater  side effects.  An ultrasound study must be carried out several weeks prior to the implant to determine if it exceeds 60cc in volume.  If so, then patients are encouraged to begin a course of hormone blockers for at least 2-3 months to shrink the prostate to less than 60cc.  The complication rates increase significantly for a prostate gland greater than 60cc.

Your Urinary Flow
Patients with significant urinary flow problems will have a higher probability of urinary complications with the procedure.  Urinary flow can be measured many ways but the simplest is using the American Urinary Association (AUA) Symptom Score.   Patients with AUA < 20 are the best candidates for seed implantation.

to determine your AUA score.

Your Type of Prostate Cancer
Prostate seed implants are most effective for early stage of prostate cancer.  Typically, seeds alone are most effective in patients with low risk prostate cancer and in some intermediate risk patients.    Even if a patient is not a candidate for just seeds alone, it may be combined with radiation therapy and/or hormone blockers depending on the patient's PSA, Stage and Gleason score.  

  to go back to the definitions of Prostate Cancer Stages, PSA or Gleason Score Definitions and Low, Intermediate and High Risk Prostate Cancer.